Does Hard Drive capicity affect performance?

[crisito]

As above, does the size of the hard drive and the storage space used in the hard drive slow a Mac down after it gets more full?

For example, if I am using 150GB of a 160GB hard drive, would this slow it down compared with being only 70GB filled?

 

[Tallest Skil]

You can only notice a slowdown with 10 or fewer gibibytes free, as you said.

It's a... moderately arbitrary line, but before that, there really is no noticeable slowdown.