Confirmed (= as seen on youtube) setups working plug&play with High Sierra beta
Akitio Node + amd rx580
Akitio Thunder2 + amd rx480
of course Apple devkit (Sonnet Breakaway Box + amd rx580)
no hack of any kind required, just log out and log in
fun fact: they work even before High Sierra is installed, already in the install wizard (AMD cards of course, not nvidia)
So, pretty different from Sierra.