The only thing to keep an eye on is the python version. At present, El Capitan has the latest python 2 (2.7.10) but I've seen Mac OS lag behind the versions available from places like macports in the past. Also, if you're using python 3 you'll need to get that from elsewhere and install it. If you're just a casual user, however, you're probably using python 2 and will be OK.