As the title says - over time it seems the mouse shortcuts stop working (such as mouse 4 or mouse 5) but the keyboard shortcuts continue to work. Has anyone experienced this? The only fix is restarted... I tried a sudo killall dock but this doesn't fix it. Here is how it happened last time: I opened handbrake I pushed mouse 4 to show all four of my desktops The "choose a source" dialogue box opened up and was at teh MIDDLE of the screen - in front of my 4 desktops It took a while and I couldn't really click on the dialogue box but eventually it worked I chose the source, hit ok, chose my desktop, and mouse 4 stopped working Edit: Something odd (maybe normal?) - in firefox pressing mouse 3 (middle button), mouse 4 or mouse 5 all has the same result of showing the scroll icon. Anyone have any ideas on how to reset this?