I also switched from an HTC android Incredible to a 4S, 16GB.
Bought mine in southern Maryland. Got to the store at 8 am, and there were about a dozen folks in line in front of me, less than I expected.
I expected there to be differences between my Droid and the 4S and of course there are. Some improvements, some annoyances I haven't resolved.
One of these is how long the display stays lit on the 4S if there is no activity going on...this was adjustable on the Droid. I haven't found the adjustment if there is one on the 4S.
The other is syncing regularly with my Gmail contacts. Doing so is counter-intuitive and involves using iTunes on my computer. Yikes! What a messy solution.
I also haven't figured out how to adjust the volume settings for the various signals and warnings.
It would be nice to have "widgets" on the home screen to turn Wi-Fi and Network on and off, and save battery time without having to drill down through menus. Also, I've found no "Call Blocker" that will work without jailbreaking the phone, which I do not want to do. Suggestions?
There also was a good signal strength meter available on the Android called Real Signal. Haven't found one yet for the 4S. And where is the PDANet app?
I do like the look and feel of the 4S.