Here's the deal, I got my MacBook Pro a few days ago. After it goes to sleep or after extended use the F1-F12 keys are not functional. I believe this is a software issue, because holding Fn, I can access things like screen brightness, volume, etc. But the only way I can solve this issue right now is to reboot, which is an inconvenience for me. EDIT: They do work. I found out that all the hotkeys were reset. For some reason. ... help?
10.5.1 EDIT: I think I know why now. It's because of WoW overwriting the keybinds? can I prevent this some how?
this is a leopard bug. the keyboard shortcuts for exposé, dashboard and the mini dictionary seem to disappear. it happens to me after i use time machine to restore a file. hopefully 10.5.2 will resolve this.
Go to System Preferences->Keyboard and check to see if the FN keys are on. If you combine FN with F1-F12 keys it will work, but you can uncheck it in system preferences.
Supposedly there was a firmware update that fixed this issue for some people. And no, WoW doesn't touch your system preferences.