just the fact that QWERTY layout was designed to slow down the typing speed...
I didn't know that! Why would they design it to slow you down?
Almost. QWERTY is not designed to slow typists down - it's designed so that the most common letter sequences do not result in adjacent key presses.My understanding was that typewriters kept jamming because people were typing too fast on them, so they changed the typewriter layout to QWERTY to slow down the typing. Now we have QWERTY keyboards everywhere simply because it was carried over from typewriters.
Getting your brain to learn the new shortcuts (Ctrl+c, Ctrl+v, etc) is the same and getting your brain to learn new letter positions. To me, copy and paste are just as easy as they were in Qwerty.
They are two handed for me now, which seems easier to me actually. In Qwerty they are one handed... which is like using the left Shift key to make a capital A, S, D, or F... you should be using the right Shift key for those letters (in Qwerty of course).