File Splitter & Combiner

It sounds like the file may be larger than 4GB and the drive is formatted as FAT32. If that's the case, format the drive as HFS+ or NTFS or exFAT.

Format A Hard Drive Using Disk Utility (which is in your /Applications/Utilities folder)

Choose the appropriate format:

HFS+ (Hierarchical File System, a.k.a. Mac OS Extended (Journaled) Don't use case-sensitive)

• Read/Write HFS+ from native Mac OS X
• Required for Time Machine or Carbon Copy Cloner or SuperDuper! backups of Mac OS X system files.
  [*]To Read/Write HFS+ from Windows, Install MacDrive
  [*]To Read HFS+ (but not Write) from Windows, Install HFSExplorer
• Maximum file size: 8EiB
• Maximum volume size: 8EiB
• Mac OS X: Mac OS Extended format (HFS Plus) volume and file limits
• You can use this format if you only use the drive with Mac OS X, or use it for backups of your Mac OS X internal drive, or if you only share it with one Windows PC (with MacDrive installed on the PC)

NTFS (Windows NT File System)

• Read/Write NTFS from native Windows.
• Read only NTFS from native Mac OS X
  [*]To Read/Write/Format NTFS from Mac OS X, here are some alternatives:
  • For Mac OS X 10.4 or later (32 or 64-bit), install Paragon ($19.95) (Best Choice for Lion and Mountain Lion)
  • For Mac OS X 10.5 and later, including Lion, FUSE for OS X
  • For 32-bit Mac OS X, install NTFS-3G for Mac OS X (free) (does not work in 64-bit mode)
  • For 64-bit Snow Leopard, read this: MacFUSE for 64-bit Snow Leopard
  • Some have reported problems using Tuxera (approx $36).
  • Native NTFS support can be enabled in Snow Leopard and later versions, but is not advisable, due to instability.
• AirPort Extreme (802.11n) and Time Capsule do not support NTFS
• Maximum file size: 16 TB
• Maximum volume size: 256TB
• You can use this format if you routinely share a drive with multiple Windows systems.

exFAT (FAT64)

• Supported in Mac OS X only in 10.6.5 or later.
• Not all Windows versions support exFAT. See disadvantages.
• exFAT (Extended File Allocation Table)
• AirPort Extreme (802.11n) and Time Capsule do not support exFAT
• Maximum file size: 16 EiB
• Maximum volume size: 64 ZiB
• You can use this format if it is supported by all computers with which you intend to share the drive. See "disadvantages" for details.

FAT32 (File Allocation Table)

• Read/Write FAT32 from both native Windows and native Mac OS X.
  [*]Maximum file size: 4GB.
• Maximum volume size: 2TB
• You can use this format if you share the drive between Mac OS X and Windows computers and have no files larger than 4GB.

 

Or exFAT which doesn't require any drivers but XP does require a patch from Microsoft.