This has been around for a while, and is something that really irritates me. It happens on odd occasions too, so not sure how to replicate it. Anyway, this is what happens. Say I'm browsing in Safari, I'll be unable to click on my desktop. Only way to be able to do access Finder is to CMD+Tab to it then it all works fine. It'll happen in any application and on odd occasions - sometimes I'll open a folder in Finder, then go back to another application and I can't click on that folder or on the desktop. It'll just remain in the application. This has happened consistently throughout Leopard and isn't specific to me - my previous gen MBP did this, and on a fresh Leopard install it happens randomly. Anyone else experience this?