I updated my late 2013 15" MBPr to El Capitan 10.11.1, and my Focusrite Saffire pro 40 stopped working. When I plug the interface into my laptop it isn't recognized in the Audio panel in system preferences as an available I/O interface. I'm using a Firewire 400 to 800 cable and the apple thunderbolt to firewire 800 adaptor. Things were working great until I updated from 10.10.5. I also have a 2011 iMac still on 10.10.5, where the same interface and cable combination works without any problems. I'm using the Focusrite Saffire mix control 3.6 drivers, which Focusrite claims work fine on 10.11. Does anyone else have their Saffire Pro 40 working on any flavor of 10.11? Any suggestions?