I prefer the larger size. I rarely hold it in my hands for an extended period. I usually have it sitting on my chest and just use a hand to balance it. I have used it for hours this way without issue... It was easy with an iPad 3, but even easier with the lighter weight of the Air2.
I should mention that the mini has never had any appeal to me because I would never walk around with it in a back pocket and if I have to carry a bag, I would rather have the larger screen when I got it out. I like editing photos, reading magazines, watching video, etc... And those are all better with a larger screen.
I now have an iPhone Plus and it fits easily in my front pockets, so I have that for portability.
I should mention that the mini has never had any appeal to me because I would never walk around with it in a back pocket and if I have to carry a bag, I would rather have the larger screen when I got it out. I like editing photos, reading magazines, watching video, etc... And those are all better with a larger screen.
I now have an iPhone Plus and it fits easily in my front pockets, so I have that for portability.
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