That's a nice board. It just lacks in the overclocking department since you can't make vcore adjustments. Here's how the performance/cost breaks down:
e5410 = 8.67MHz/$1.00
e5420 = 7.37MHz/$1.00
e5430 = 5.50MHz/$1.00
Since you're less likely to get high overclocks using the ASUS board you'd be better off setting your goal at 2.8GHz and buying the e5410 which would net you the highest performance/cost ratio. All the reports I've read indicate the the e5410 reaches 2.8GHz on stock cooling with no problem and with no need to increase the vcore (which you wouldn't be able to do with the ASUS board).
If you'd like to go higher than 2.8 and try to match or exceed the performance of a 3.0GHz or 3.2GHz Mac Pro then you'd probably be better off getting the Skulltrail board since you'll more than likely need to up the vcore. Also, If you're shooting for 3.2GHz or higher then out of those three chips you probably ought to go with the e5430.
Overall, I'd be a bit hesitant to spend that kind of money on parts with Nehalem just around the corner. If you played your cards right you could have an OSX Nehalem machine before the release of the updated Mac Pros at less than the cost of a new Mac Pro which also might perform better with some overclocking.
Just my $0.02