hay I just got a macpro 3.1 (osx10.7.5 at the mo but happy to upgrade if needed) and I want advice on what GPU to buy for use with video apps. I know final cut 7 makes almost no use of GPU so it's not a thing there. Im looking at learning adobe After effects CS6 and maybe Adobe premiere Cs6, at first I had the idea/impression I needed a nvidia card for use with AE Cs6 but after a looking at the Adobe help site im slightly confused. Adobe premiere = CUDA (for somethings not all) After effects = any GPU? open GL/CL (with 1GB of ram or more) Ill also be having a go at the motion which i assume is ok with any card? i was looking at the nvidia GTX 550 TI (as it's on sale at the mo) or the GTX640/650 (leaning towards the GTX 640 as it's cheaper) but id be happy to look at ATI cards if you think there a valid option. and is vRAM important once you get past 1GB (for some one staring out/learning)? info on openCL use in premiere http://blogs.adobe.com/premierepro/2012/05/opencl-and-premiere-pro-cs6.html only; " Fast Blur effect Gaussian Blur effect Directional Blur effect Basic 3D effect " cant be done in openCL and are left to the CPU the rest can be done on openCL it seems but are done with a CUDA card (tho dont know if CUDA vs openCL will give a big speed change). info on After effects http://blogs.adobe.com/premierepro/2011/02/cuda-mercury-playback-engine-and-adobe-premiere-pro.html 'Only the ray-traced 3D renderer in After Effects CS6 uses CUDA (as do a few third-party plug-ins).'