Look, theoretically u can do this:
Make 2 partitions using the Disk utility, and format the one of them as HFS+ and leave the second as is, unformatted, then use a windows box and format the 2nd partition as NTFS
But thats in theory, in practice when u hook up that 2 partition disk on windows, widows wont see anything in it and ask you to format it, all of it, dont!
You need to use a program like MacDrive in windows to make them "see" the HFS+ partition and then move one formatting the 2nd partition as NTFS
but! In order to confuse you more

u have to think first, do you really need an NTFS partition? the only advantage would be the ability to put files in it that are larger than 2GBs per file. And Im talking about the situatiation of having one single file thats its size is larger than 2GBs in size. And thats almost never a limitation, even in the raaare event that you have such a file, you can always split it in 2GB zip/rar files
But then again! the by faaaar best way to do this is making one huge HFS+ partition, harnessing all its benefits, and then when u need to hook it up to a windows box, use MacDrive for windows to access it asif it was an NTFS dive
