Since Half Life or any game can take advantage of one or two CPUs plus the Intel Itanium 2 is a very poor performer when running 32-Bit Windows Programs. To summarize: terrible frame rates.
Except it isn't tightly integrated like a NUMA machine is. Each Xserve can only access it's own local memory and discs. Big iron like this really is different; a 512-cpu NUMA machine is hardly the equivalent of 512 PCs. Individually the PCs may be faster at some things (like integer computation). Considered as a collective they're often a lot slower, especially on I/O (where the PCs get their heads handed to them) and on data sets too large to fit in a mere 4 GB of RAM (note the Altix maxes out at 48 GB per cpu).