You can certainly try it out yourself. If there's no change for you, then just change it back. It won't hurt anything to try it.
I do see some apps that allow you to change the language in the app's settings.
If it is a specific app, from another developer (not Apple), then have you considered contacting the developer to see if they have some way to help you out?
Yes, you can rearrange the languages as you like, and change it later again if you wish. If I remember correctly, the device will reboot after you change the order.
The preferred language order affects all apps, so you can't set it for a single app.