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Keeping the current Mac Pro design, it would use a Blade server type structure with each of the 3 boards supporting a CPU socket, 2 DIMM slots and an M.2 slot. A taller version would be available to provide GPUs to fit on the bottom base.
 
Keeping the current Mac Pro design, it would use a Blade server type structure with each of the 3 boards supporting a CPU socket, 2 DIMM slots and an M.2 slot. A taller version would be available to provide GPUs to fit on the bottom base.
Current Xeons have quad channel memory, so fewer than 4 DDR4 DIMM slots per CPU socket is leaving performance (and capacity) on the table.

8 to 12 DIMM slots per CPU is more typical for workstations and low end servers.

And M.2 is very old tech, more current would be PCIe x4 NVMe storage.
 
Current Xeons have quad channel memory, so fewer than 4 DDR4 DIMM slots per CPU socket is leaving performance (and capacity) on the table.

8 to 12 DIMM slots per CPU is more typical for workstations and low end servers.

And M.2 is very old tech, more current would be PCIe x4 NVMe storage.

I haven't done the sizing, but I don't think the boards have enough space to fit more than 2 DIMM slots along with an M.2 slot.

M.2 supports PCIe x4 NVMe storage. It is only a connector.
 
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