Of course.
Boot to Mojave installer.
Run "Reinstall macOS", choosing your
other drive as the destination. Could be internal on a different slot in your cMP, or external. This will be best, I think, on a blank partition, or an erased drive, whatever you have. That gives you an absolutely clean install. Then, if you like, when it begins a new-user setup on that drive, you will have the choice of migrating from another drive. You can then migrate from your High Sierra drive, leaving your High Sierra drive untouched, and your
new system with everything from the High Sierra system drive, upgraded to use with Mojave. Or, just ignore the migration screen, if you want a simple/clean install of Mojave.
BTW, the Mojave install will automatically change your blank partition to APFS. There's no need to reformat that yourself, the Mojave installer will take care of that for you. It will not change the format of other partitions on that same drive (if you have other partitions on that other drive

)