It's probably a good idea to insulate, depending on the use you have planned for this space.
You'll need an air gap above the insulation if you have venting in the attic space. A 1" air gap is sufficient for this. If you do this, you will have to make sure that there are vents in the blocking between each truss, and that you rig your insulation such that the air coming through those vents only goes above the insulation. You'll also have to ensure that each truss bay has a continuous air path from one side to the other. Additionally, you'll have to seal the edges of the insulation to the trusses somehow to ensure outside air does not leak through. If you are installing drywall under the trusses, this will be sufficient.
Your other option, of course, is to install a ceiling on the truss bottom chord, and insulate above that, leaving the attic area completely vented. If you've got trusses (unless they're scissor trusses or something like that) you've already got a flat surface for a ceiling.