Microsoft has publicly stated that they will support Intel Macs with both Virtual PC and Microsoft Office. Whether or not they'll release free updates or require paid upgrades to newer versions remains to be seen. I have a feeling that Office will work just fine in Rosetta, but VPC really needs to be made in a native version, possibly even a complete rewrite or port of the PC version for it to work well. Of course, if they do that, it should be possible to make it so that emulation in Virtual PC is just about native speed because no CPU emulation will be necessary.