Obviously, without knowing the internals of the Mini 6 and Mini 5 it is impossible to know.
But these things I know...
- This issue is NOT due to a screen having a 60 Hz refresh rate
- This issue is NOT prevalent on other iPads in past or present
- People are already entrenching themselves into two extreme camps (spending a lot of time defending their position)
- If the root issue is software-based, Apple will release a fix
- If the root issue is hardware-based, Apple will deny, delay, defend
None of the iPads I've owned (and I've owned many, starting with the 1st gen) have ever exhibited this symptom (in portrait or landscape mode)
I believe that the root issue is not entirely software or hardware. I think it is a combination. The Mini 6 is a new form-factor. It isn't just a refreshed Mini 5. Although it has the same dpi density, the display panel is a different size and not simply using the panels from the Mini 5.
I suspect that Apple's engineers took the opportunity to tweak the design slightly (compared to the design of the Mini 5 panel) to reduce the cost of manufacturing. There may be some timing differences that need to be adjusted for in the drivers for the panel.
If this is true, then the question becomes, "can iPadOS be tweaked to completely overcome this issue?" If so, then the problem will be corrected with an iPadOS update. It may not be possible to completely eliminate the issue, so an iPadOS update might only reduce the effect.
I'll say it again... if a person's Mini 6 is exhibiting this symptom AND they're dissatisfied with it, then return the device for a refund...and don't question a person's intelligence if they aren't dissatisfied. I don't recommend exchanging it for another unit that may exhibit the same symptoms... or maybe it doesn't at the moment but then develop it later on (without knowing the root cause it might be possible).
If a person's Mini 6 is exhibiting this symptom AND it is not a problem for them, then be happy and enjoy your device... and don't try to minimize the issue to justify why it's not a problem for you.