I have a 6 and had a 5S... I found the 6 harder to hold and I don't really care for how thin it is I ended up going with a case to give it more of a 5S type shape. Before that I had the iPhone 6 leather case. Screen size though the 4-inch never did it for me, it was just odd, felt too long (thin and tall), only upgraded from the 4S to 5S cause the battery on my 4S just felt like it was slowly fading away.
If you like the 5S then the 5SE should handle the same. It takes some adjustment going to the 6 size width for one handed operation its still not as easy as the 5S but at least its not the Plus width, but I wanted the larger screen and it feels just right vs. the 4-inch screen which just seems squashed horizontally.
If you like the 5S then the 5SE should handle the same. It takes some adjustment going to the 6 size width for one handed operation its still not as easy as the 5S but at least its not the Plus width, but I wanted the larger screen and it feels just right vs. the 4-inch screen which just seems squashed horizontally.