I have an early 2009 24" iMac with a DIY Fusion Drive (Crucial M4 256GB + Seagate 2TB HDD) and have some issues with iPhoto in particular. Performance of launching iPhoto improved with the fusion setup, but the quitting of the app still takes 10-15 seconds. If I create a brand new library it opens and closes in the blink of an eye. I am not sure if this is just how iPhoto behaves when you have 49k photos over 190GB or not with a fusion drive setup. On a 2013 MacBook Air iPhoto closes instantly with about 30k photos in my Dad's library. I have rebuilt the library with iPhoto Library Manager but still the performance is the same. Aperture closes instantly and shares the same library, so I am not sure what the deal is with iPhoto. Any ideas?