Yes, I'm running OSX 10.4.10 and iTunes 7.4.1. The ONLY way I can get my iPod Touch to sync with iTunes is if I have it unplugged and iTunes unopen. I plug in the Touch and iTunes opens, then starts to sync. If iTunes is open and I plug the Touch in, it freezes iTunes and I have to force quit. If the iTouch is then still plugged in and I launch iTunes, it freezes and I have to force quit. The only thing I can think of is that it's yet another iTunes bug (though doubtful since no one else is reporting this) OR it's an issue with plugging it into a USB 1 port since I don't have USB 2 on my 6-year-old G4. Ideas?