I'm guessing this is some sort of built in protection, but it seems like even when I slightly move my hard drive lets out a loud click. Gets annoying when I'm sitting on the couch and it clicks every 30 seconds.
There are ways of disabling it, but its there to protect your data so I would probably keep it on.
However, it should only react to sudden changes in acceleration so if it is doing it at even the slightest move you might want to get it looked at
Mine clicks when I lift it up and tilt it. I have read that this is to help keep your data safe. I never heard it on my buddies 15" 2010 high end pro even though they have the same size and speed hard drive.