It really depends on what you are looking for and your experience level. If you are experienced with common web hosting.. any service will be bit better of a deal money wise.. but if you want simply, no brainer syncing into your iweb, iphoto, ical apps.. the ability to sync your safari settings, bookmarks, mail prefs, etc... as well as have a nice clean area to have public folders and online storage without having to do the setup yourself... go for it.. mobile me is great for that..
I have an account simply so that my staff members can have a nice easy robust public folder to use without having to ftp in, etc. This keeps me from getting any staff member up to speed with anything more complex. As well, all Macs updated and sync calendars, bookmarks, mail accounts, etc through our MM account.. so just makes a few of our tasks a little easier.
But for all my web hosting, and serious programming efforts... I use GoDaddy as suggested above..
Good deal if you want simple and no work to it. Otherwise, can set up your own environment if needed, cheaper.