Firstly, this has ALWAYS happened to me, on my iBook, and now on my Mac mini. So I know it's not a system-specific issue. The issue? After a while, QuickTime suddenly decides to stop communicating with Safari, and nothing short of a full reinstall of QuickTime Player fixes it. And after a while, it will inevitably happen again. BUT it works perfectly in iTunes. Here's an example: I want to watch the Sin City trailers. The first link is through Safari, here: http://www.apple.com/trailers/miramax/sin_city/ Clicking LARGE in the Trailer 1 column, I got this: Now, going to the same trailer with iTunes: itms://www.apple.com/moviesxml/s/miramax/1233/index.xml It works beautifully: Now... WHY is this happening? Anyone experienced this?