USB devices seem to be the issue
I tried the advice of landofiz, and it seems to work so far: I'm using Time Machine with a USB Hard Drive, and once I unplugged the drive, the iTunes plays normally. Before that, it was stopping every few minutes, and I needed to pause/play or move thru the track to get the sound back.
I'm using iTunes 10.5.1 on MBA 1,6GHz and Mac OS X 10.5.8, playing on my stereo thru Airport Express.
As a troubleshooting step, try unplugging all devices from your machine to see if one of them is the culprit.
I tried the advice of landofiz, and it seems to work so far: I'm using Time Machine with a USB Hard Drive, and once I unplugged the drive, the iTunes plays normally. Before that, it was stopping every few minutes, and I needed to pause/play or move thru the track to get the sound back.
I'm using iTunes 10.5.1 on MBA 1,6GHz and Mac OS X 10.5.8, playing on my stereo thru Airport Express.