Well...nice generalizing assumption. I bet that's why the iPhone (small) still sells like hotcakes there.
Also, if you try to hold a phablet with it resting against the palm of your hand with thumb/pinky on either side, it does fit. But true-one-handed use is difficult.
My hands are smaller, but I still like the iPhone over all other phones.
Also, regarding how to hold it...thumb on left, four fingers on the right, holding the phone?