I bought a mac pro a couple months ago, ran the OEM installed operating system, and downloaded normal software such as Adium and Burn. I also use the Apple keyboard and mouse, so I figure this must be some sort of Leopard bug, but I have yet to read about it. I can just be chatting on Adium or browsing on Safari and all of a sudden, Leopard stops receiving mouse input. When hovering over an application on the dock, the name does not come up, when pressing a button, the click does not register, etc. I can move the cursor still and switch between applications using command tab and closing them, etc. The keyboard still works fine, but the mouse does not. I tried switching mice to a Dell mouse, but the same problem occurs, so I doubt it is a mouse issue. This just happens out of the blue. Last time it happened was after I switched Spaces using control + right arrow. Again, the issue that occurs is that I can no longer use the mouse. I cannot scroll with it, I cannot click buttons; all I can do is move the cursor, rendering the mouse useless. The only solution I have found to this periodical problem is simply quitting every program using command q and command tab to navigate to them and then using the shortcut to log out and in. Has anyone found this problem or know any solutions?