You have to do what's comfortable obviously but I think this is bizarre... I mean HiDPI is designed for screens with high pixel density (like 4K on a 27" display). Pixel density is certainly not a problem on a 65" screen so it must be too far away.
From what I've read, 40" seems about ideal for 4K at desktop viewing distances... which would be about 24" away (arms reach). Some people get by with 4K on 32" displays at 24" away. So if you double the size of the pixels (as is the case with your 65" screen), presumably your monitor would look ideal at around 36-48" away.
People work with dual 27" displays (which is a combined 54") at arms reach and don't find that overwhelming, but you find this screen overwhelming at 36-48" away?
There must be a distance at which this screen feels exactly the same as working on a 32" or 40" 4K display at arms reach.
And of course, the downside to running HiDPI is that you're throwing away screen real-estate... in this case, for no good reason that I can see.