Do it! I did it 7 years ago, Windows is a mostly foreign OS to me now despite having to use it at work on occasion.
Most Win apps have equivalent of better apps on the macOS platform, including MS Office. Don't let the initial cost of Macs scare you, the build quality is generally more in line with professional grade PC (as opposed to the cheap consumer grade machines that sell for half of the price of a Mac). Get used to searching for "Mac equivalent of X" to find Mac apps. Understand it may take 6 months or so of daily use to get into the comfort zone, every day you will find yourself trying to figure out how to do something that you used to do on PC.
Apple has some good resources to help in your journey. Apple Stores offer free classes on Mac, and they have web help to guide PC users making the switch. Given your familiarity with iOS, watch, ATV, most of the concepts are already familiar to you. And don't be shy to ask on this, or other Mac oriented forums, the community is generally quite helpful, particularly if you start with the admission of being new to the OS.
That said, as
Rok73 suggests, a little bit on how you use your PC might help the community to guide you.
Mac is not for everyone, but will be an excellent choice for the majority of PC users. Keep in mind, there are just some things that Macs cannot do, particularly in the corporate world where IT shops have built Win-centric solutions. But, even if there are one or two of these, there are ways to get around the limitation with Virtual Box (Free), VMWare Fusion, Parallels to run WinOS VMs on your Mac desktop. Or, as
SpinalTap suggests, partition the HDD and install Win10 in BootCamp, so it will be there in a pinch. Just a reboot away!