I have the G5 (the mouse) on my Macbook and using USB-overdrive to cutsomize the buttons (I have buttons for F9 F11 and F12, doubleclick, COMMAND+W) so I can use my computer without having to have one hand on the keyboard all the time.
The only bad thing is, USB-Overdrive does not support the 2000 dpi of the mouse (or some other thing as frequency or whatever). I like having my mouse on an extremely high speed without any acceleration (can you disable the acceleration is OSX somewhere?), one half square inch is what I have for covering a 20" wide screen. It's actually very comfortable, the palm rest on the table and the mouse is moved by the fingers. Other people can't use my computer cuz the cursor is moving so fast for them they are always asking "where is the cursor" while bashing the mouse against the table like when a secretary is surfing the web on the slowest possible mouse speed. And my OSX windows close (Command+W) when you push the mouse wheel to the right (it's very sensitive) so it's hell when you're not used to it I guess. 🙂
I don't have the smooth mouse movement (pixel per pixel precision) on fast settings, it makes little jumps that make it almost impossible to select a single letter in this text area for example. OSX supports the mouse itself, but you can't customize it at all. If someone has a solution for me, please help. I love this mouse and the tuning weights, lots of buttons, teflon pads etc.