A 4x Max Mac Pro would have some clear potential hardware advantages and disadvantages vs. a PC workstation.
The PC hardware advantages are in the upper-end configurations, and could be addressed if Apple offered add-on RAM and GPU modues. In deciding on this, Apple will certainly look at what percent of its current Mac Pro sales use the highest RAM and GPU configurations.
Hardware advantages, Mac Pro
- Extraordinary efficiency
- Quiet operation
- Task-specific hardware acceleration, which makes those specific operations run unusually fast
- High single-core speeds, especially during multi-core operation, when compared to high core-count Intel Xeon and AMD Threadripper chips (the latter need to have reduced clock speeds to avoid overheating, particularly when all cores are running; that's much less of an issue with AS). This would give much faster operation for multi-core apps that can only utilize a limited number of cores.
- Unified memory gives the GPU access to unusually large amounts of RAM
Hardware advantages, PC workstation
- Much higher maximum RAM (unless Apple offers add-on RAM modules). A 4X Max will have 256 GB; Ice Lake can have up to 2 TB. Not sure about Threadripper, but it looks like its max is 1 TB.
- Much higher maximum GPU performance (unless Apple offers add-on GPU modules). A 4X Max should have performance about comparable to a single A6000 desktop chip. Current PC workstations can be configured with up to three of these.
There are also clear software advanatages and disadvantages to each, which aren't addressed here.