Can you elaborate how biotech depends on Intel macs? I have worked with aerospace and defense companies so I'm familiar with certification processes for software and hardware. But even in there, they could do quite a bit in two years. I expect a similar situation for biotech.The biotech industry is a big user of Intel Macs and there are a lot of tools that are simply not ready for M1 and it will probably take a couple of years to get them ported, running and certified. It's not really an industry any vendor wants to lose.
Aside from such certification situations, my impression is that most professionals who need x86 need it for either legacy software or for simulating user environments. Both cases can be overcome easily with VMs at work, through a vpn or in the cloud. It's the route me and some colleagues are taking. That leaves gamers and we all know Apple wants them on their OSses, not via bootcamp on Windows.
Apple has it all figured out. Intel macs are going the way of the dodo.