@CarManDSL "I will also be changing GPU to Vega 64 which supports up to 8k@60 via 2xDP outputs, ignoring TB completely."
Vega series GPUs were one of the last AMD graphics cards that do not support DSC.
I think DSC support only came with the RX6000 range?
As
@joevt explained in the post above (#36), 6K monitors like the Asus PA32QCV (6016x3384) when not using DSC need 38Gbps to run at 6K.
A single DP1.4a output can only achieve 32.4Gbps maximum, so can't drive a monitor higher than 5K if the GPU doesn't support DSC.
The solution at the time (2015-) was to use two DP cables from the GPU to two DP inputs on a single monitor.
Only the Dell 2715K (5K) and the Dell 3218K (8K) monitors supported this dual-DP cabling mode, as well as a DIY conversion board for the 5K iMac (R9A18).
(Apple of course did their own thing with a single cable dual-channel TB3 mode for 5K iMacs and the 2019 MP)
With the introduction of DSC, single cable operation using TB4/USB3/4 cables became possible.
"I may find full 6K too small on the screen and scale to a more comfortable text size. Does this play into less bandwith needed to light up the screen, even if at a lesser resolution?"
Apple 4K iMac, 5K iMac and ASD or 6K XDR Pro monitor all default to displaying the Menus and interface and text elements at exactly half the pixel resolution of the panel.
Apple call this Retina HiDPI, where each Menu or text pixel is displayed on the screen by 4 panel pixels.
Graphical elements like screen images and video are still displayed at full resolution.
So 4K video is shown at 4K etc.
This takes as much bandwidth as if the monitor is running at the highest 6k resolution.
"Does a GPU need to support a monitor at it's max resolution to even light up, even if scaled down?"
No. The computer reads the monitor's EDID (identity info) and adjusts the GPU's output to match what the monitor is capable of. The monitor will display the highest resolution screen raster that the GPU and cable bandwidth is capable of supporting.
Or anything smaller...