XFX cards are notorious for not working on the mac...further I'm not sure that card has native support? Let's wait for someone else to chime in for sure. @theitsage ?
@3587 Re-seat the RX Vega 64 in the slot. I got an XFX RX Vega 56 yesterday and it was a bit of a challenge to get the two feet of the GPU in place. Once it's fully situated the card should work with High Sierra beta. These RX Vega GPUs are all reference design so there's no difference between brands. The AIB cards later on will make a difference in terms of macOS compatibility.
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Yes it was running in internal display mode, AMD XConnect in Windows 10. You can read more about the setup process in Bootcamp here.
The drivers for RX Vega in macOS High Sierra are not running well. Closer to the iMac Pro's launch is when the drivers are ready. Also, the 550W PSU in the Mantiz Venus can be overwhelmed by the RX Vega 64 power draw.