Unfortunately this isn't possible: while there are measures for boot-selection persistence, OpenCore needs to be selected before it can actually do anything.
Properly blessing OC can be a major hurdle on a Mac Pro 5,1. If no boot volume is blessed, the Mac will just try to boot something. Unfortunately, that could be an unsupported installation, which will cause the Mac to hang and then shutdown. Luckily, there are several options to get out of this predicament.
One option is to physically separate supported from unsupported installations. By removing the disks with unsupported installations, the Mac should be able to boot natively. To bless OC, it is then just a matter of restarting into recovery as described in part 1 of the
guide (see "First Boot").
If OC is installed to an EFI partition, then there should be no problem blessing it from Mojave's recovery mode.
As
@Macschrauber pointed out, another option is to use an EFI (flashed) graphics card to bless OC from the native boot picker. In fact, blessing OC like this is the standard approach for all Macs except for the Mac Pro.
A third option is to create an emergency OC CD. Yes, a CD. The reason for a CD is that holding "c" at boot tells the Mac to boot from the CD. Unfortunately, OC hides any instances of itself, so blessing OC directly from the OC boot picker isn't possible. However, it is still possible to boot into recovery and bless OC from there. Note that the OC CD should be configured with
RequestBootVarRouting turned off, otherwise the main instance of OC will not be blessed properly.