It should, technically it is a stereo headphone OUTPUT and mic INPUT. You need a 4-pin plug to take full advantage of it. If you use a regular TRS or TTRS (2 or 3-pin) plugs, then chances are, it won't work because it is not making proper contact with the pins. You can get a cheap converter to be sure, if your mic does not work by itself. It also depends on the type of microphone. Some requires phantom power. Those ones won't work without some kind of a converter/adapter device that also injects power.