I have a Lacie Rugged firewire 800/400/usb HD, and I've tried every possible combination to no avail. My MBP just won't pick up the drive. It does not appear in disk utility either. Even stranger is that when I plug it in via USB, it makes a clicking sound! Surely the sound of a dead drive no? But I've tried it on several other machines and they seem to mount it flawlessly, so I guess the drive works- (for now). So I assume it's a problem with my mac... and I don't know what to do... help!