MBPr screen resolution issues

First post and first apple computer so excuse the ignorance. I purchased a rMBP or MBPr whatever the short version of its called and had a question. I downloaded a few programs and I'm having trouble getting them to fit correctly into the screen. Its a 15' if that matters. Trine and a few other full screen apps are pretty horrible. Either the program is way too big for the screen or its not sitting even in the monitor. I was hoping there was a way to have the macbook auto resize to the screen resolution of the program? If that makes any sense. Thanks everyone.