Multiple Drive Backup Solution - Time Machine?

I currently have the follwing drive setup on a Mac Pro (early 2009) and am looking for any suggestions for an effective backup software solution as described below:

DRIVES REQUIRING BACKUP
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- Drive-1 (internal): El Capitan 10.11.6 (OS, Application files and Working files) / Plan to just continually backup to an external 2TB drive
- Drive-2 (internal): Snow Leopard 10.6.8 (OS and Applications only) / Only looking to back up ONE clean instance of this drive preferably to a Time Machine Backup to a small external drive only connected when manually doing a one-time Time Machine backup or in the future when any changes are implemented to the software applications (i.e. plug-ins, updates, settings). Will only be using this Drive to use applications from time to time and will be saving work files to another external drive
- Drive-2 (500GB internal) - Will be used for Work Files Storage. Looking to backup this entire drive to another 500GB internal drive
- Drive-4 (500GB internal): Used as an internal Photoshop scratch drive and as a backup drive for Work Files

I am under the impression that Time Machine can not be used to do multiple types of backups as I require above. Can anyone recomend a good file backup scheme for getting the above done. I am willing to forgo using Time Machine as my primary OS drive backups if installing a Third party App such as Acronis True Image if it will do all the above while alowing for "scheduled" backups of the same (excluding the occational Snow Leopard drive backup I will be doing manually).