If you are going to be attaching hard drives to the hub, most USB 3.0 hubs have issues connected drives to a Mac (especially SSDs). They are usually fine for keyboards and syncing i devices. But their firmware doesn't support standard USB 3.0 features the Mac tries to use (i.e. a hub issue not a Mac issue). USB 2.0 is a simpler interface and typically is without issue unless a device draws too much power. Sleep is another source of possible incompatibility. Mixing 2.0 and 3.0 devices is another. Its a wild west out in 3.0 land.
The only hub I've seen so far that seems to be 100% compatible with all kinds of drives and is solid connected to a Mac running 10.8.3 is the Belkin Connect USB 3.0 4-Port Hub sold at apple stores and sometimes available elsewhere. It is a powered hub.