I almost always prefer a mouse. However, Apple has done such a good job with the Magic Trackpad 2, that I am going to soon order one. I only wish I could order the matching orange of my iMac (and that I could pay the $50 upgrade fee from the time of purchase).
I really cannot complain about the MM2. I don't have any issue using it. The gesture area feels great. I grip with my fingertips FWIW. I do however, rely on a corded Razr mouse for my job (Corp Finance / Accounting software).