Thanks to everyone for their replies & info.
I've decided to keep the Studio & just deal with the Thunderbolt issues.
Today, I ordered the OWC Thunderbolt 5 hub off Amazon, to hopefully allow me to connect all 3 Acasis Thunderbolt enclosures/2TB drives along with my 2nd Dell monitor.
I'll reply back once I get the hub & let everyone know how it goes.
Experienced a strange issue just a few minutes ago for the 2nd time today: I installed Sequoia onto the TB501 Pro Thunderbolt 5 with 2TB WD SN850X SSD earlier today & have been booting off of it. I just powered up to reply here & all of a sudden, my monitor/display lost video signal. This is the monitor that's plugged into the HDMI port. The other monitor is currently unplugged as I wait for the OWC TB 5 hub. I don't think this was a video issue though. I get the sneaky suspicion that this was related to a connection loss with the TB501 Pro running Sequoia. So I booted off the Studio's internal SSD to post this reply.
Ugh, Apple. If only your internal storage was affordable, I'd have at least 4TB SSD built in.
Another thought: If the OWC hub runs well, maybe I'll RAID 0 the TBU405 Air drives. Has anyone here tried it with external TB drives? Results?