I removed BOTH versions of Opera that were contained inside my Photoshop CS3 app. (Two different version numbers!) I also deleted the Bridge and Device Central apps and other stuff, including cutting out the PPC binary with Monolingual and pretty much getting Photoshop down to a total of 222MB (The Intel-only Photoshop itself is 118MB, the app was twice that size before losing its PPC binary.) in one folder. And it still works.
Adobe pulls some pretty stupid stuff. I had to go to a lot of trouble to trim down the bloat.
Opera is there for Photoshop's web stuff. Though why? Don't they think the user will already have a browser installed? Screw you, Adobe.