Can a PC spyware affect a Mac? A friend of mine sent me an exe file, Symantec Endpoint Protection detected a Spyware.Perfect virus. I looked up what that was and found out it is a keylogger. Every now and then I open exe files (using CrossOver) sent to me by known sources. Most times the files are clean. This is the first time I've detected something. But considering it's a PC file virus, would it still affect my system? I haven't opened it yet, and my friend hasn't experienced anything on his Mac, or detected anything. Don't think I'll be launching that file, I'm just curious more than anything else. Thanks.