I don't have time to read through the entire thread in great detail, but here's my response to the main concerns in the original post.
Firstly, modern versions of OS X use the RAM much more extensively in order to enhance overall system performance. This is mainly in the form of a file cache, so recently used (or commonly used) files are loaded into the memory so that they are loaded extremely fast when called upon. This goes along with the popular philosophy that "unused RAM is wasted RAM". If an application needs the space and its files aren't already cached, the cache will surrender its occupied memory to make room for it. In other words, it's normal for RAM usage to be high on OS X, even if you've got loads of RAM.
OS X Mavericks' enhanced Activity Monitor shows the above with much great clarity (see attached image, especially the info on the right). You can see that most of my 16GB gets used, even when the machine is idling (10GB used in the screen shot).
Secondly, from my experience with MacBook Pros with Retina display (I owned a 15" model for a few months and I'm also training as a technician at an Apple Authorised Service Provider), I've found that they require SMC (System Management Controller) resets at relatively frequent intervals. It's probably a firmware issue, but I found that these machines will sometimes slow down significantly in terms of graphics performance, such as with OP's Counter-Strike example. This is likely due to the SMC throttling performance when it shouldn't be; a reset will fix this, at least temporarily.
To perform an SMC reset, shut the MacBook Pro down and plug it into the mains power (if it isn't already). Unplug all peripheral devices. With the machine powered off, press (on left side) Shift + Ctrl + Alt + Power *simultaneously* for about a second and then release. Start the computer up as normal.
SMC reset support document:
http://support.apple.com/kb/HT3964?viewlocale=en_US&locale=en_US
I hope this info helps!