Plex has a steep learning curve. I tried it for a few hours one day many months ago and abandoned it...but eventually picked it up again and after a couple more hours of reading and research realized how easy it was to use. Once you get how it all works its really quite easy. Maintenance takes almost literally no time at all and adding new files and having them scrape all relevant information into your library is crazy easy. Much easier than itunes. Here are some screenshots of my setup as was requested above.
Main menu.
Movie section (info that is obtained automatically with near 100% accuracy - Title, Description, Poster, Actors, Directors, Studio, Rating, Run Time). Searching for all movies that you own by one actor, director, or studio is a breeze and a lot of fun.
Paused Movie screen (plus ability to select audio track (5.1, stereo, director commentary) or subtitles on/off)
TV Section (gets all show information, including artwork, episode info, rating, and air date)
Connects to itunes to get music and podcast information (my podcasts are set to auto download in itunes in the background and plex auto inserts them into my library)
Who can forget the plugins for Hulu, Netflix, Apple Movie Trailers, Colbert Report, and The Daily Show (so I can watch full episodes every night without having to download them individually or open up an ugly web browser).
I highly suggest anyone looking for an HTPC front end try Plex. It looks fantastic and is so easy that literally anyone from my girlfriend or my grandmother and even my 6 year old little brother can use it. The work required to add new episodes or movies is insignificant (rename them to a format that plex likes and drop them in the correct folder...plex takes care of the rest).
The Plex community is very active, developers are super helpful and support is great...even for Snow Leopard. I have over 2,000 tv episodes in around 20 different shows. About 400 movies scraped into there too...most of them are complete Video_ts rips. For the rare movie that plex has trouble playing there is even a direct link in Plex to launch Frontrow and all the same remote control commands work so I don't have to grab out the keyboard and mouse.
Hope this helps. Sorry for the large pics.