Drop the optical drive, but wait at least a year to 18 months. I think most people are like me and don't live on the bleeding edge.
As a Microsoft technician, all software is available to me at very low cost via download through the new Microsoft Academy, but for all others, most Microsoft stuff is only on DVD, or largely marketed that way.
Other companies still offer their stuff mainly on DVD or CD, though there may be download options.
I think by the middle of 2012, we won't be having this discussion and the optical drive will be like a 3.5" inch floppy. But the computer using world is not yet in a position to abruptly drop the optical drive.
When the optical drive is dropped, Apple will do it first just like they were one of the first to drop the floppy. So far transitions, like going away from floppy, adding USB or Firewire, or dropping ethernet cables in favor of going wireless, have been slow transitions.